Characterization of a complete immunoglobulin heavy-chain variable region germ-line gene of rainbow trout.

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Characterization of a complete immunoglobulin heavy-chain variable region germ-line gene of rainbow trout.

A germ-line heavy-chain variable region (VH) gene (RTVH431) has been isolated from a rainbow trout (Salmo gairdneri) and characterized by complete nucleotide sequencing. It is characteristic of VH, as shown by the conserved octamer and TATA motif in the 5' region, the heptamernonamer recombination signal sequence in the 3' region, and the 18-amino-acid-long hydrophobic leader interrupted by an ...

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ژورنال

عنوان ژورنال: Proceedings of the National Academy of Sciences

سال: 1990

ISSN: 0027-8424,1091-6490

DOI: 10.1073/pnas.87.19.7767